NCT06799871

RFA R-Evolution: a New Protocol to Avoid Implant Failure

Retrospective Single Cohort Mono-center Study on Trends in Implant Stability Measured by RFA

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: Daniele Moretto · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The main objective of this study is to assess the impact of confounding factors such as jaw, implant position, indication, smoking status, implant dimension, and medical history on RFA trends. In addition, this study aims to explore correlations of RFA trend, with the goal of using ISQ trends as an indicator for treatment protocol decisions (e.g. time of loading). Participants have already received dental implant as per clinic's standard protocol. Information regarding Implant Stability Quotient (ISQ) measurements performed at any time point until 1-year follow-up will be collected. The principal investigator protocol regarding the use of ISQ measure to define time of implant loading will also be assessed. Only participants followed up at least until one year after implant placement will be included in the data collection.

Detailed description

This single-center retrospective study includes all consecutive participants treated since October 2021 for single or multiple edentulous sites (either healed or extracted). Only participants with a 1-year follow-up visit and RFA measurements at three or more time-points are included. Participants will be consecutively included provided they meet all of the inclusion criteria and none of the exclusion criteria. As the data is anonymized, participants will not be contacted for consent. Any additional post-hoc exclusion of participants will be thoroughly documented. The primary endpoint of the study is: -Occurrence of RFA trends (3 consecutive increasing or stable RFA values vs 3 consecutive decreasing RFA values) Secondary endpoints: * Implant treatment success (implant loaded functionally) after 1 year of implant placement * Change in prosthetic protocol (3 months to definitive prosthesis placement in maxilla, 2 months in mandible) due to ISQ trend Participants have already received dental implant(s) at surgery visit. Implant Stability Quotient (ISQ) was assessed after implant placement. Depending on the trends in ISQ, implants were loaded with provisional and the final prosthesis and followed up at least until 1 year after surgery. Data collection methods Data will be collected by automatic extraction from the clinic's patient management system and will for statistical analysis. Implant is considered survived if it is in-situ. Implant treatment success is defined as implant loaded functionally. Demographic data will be collected in the automatic extraction of the data and used to access participant's eligibility to partake in the study. Any relevant medical history of participants will be collected in the automatic extraction as well. Demographic and medical history data will also be part of the data analysis. At interim and 1-year follow-up visits, prosthetic parameters will be collected.

Conditions

• Dental Implants

Interventions

Type	Name	Description
DEVICE	Dental implant	There is no intervention in the study. The participants have already received dental implant treatment and data will be collected retrospectively regarding the procedure

Timeline

• Start date: 2025-01-01
• Primary completion: 2025-06-01
• Completion: 2026-01-01
• First posted: 2025-01-29
• Last updated: 2025-01-29