NCT06799832

Urethral PeRfusion Index-Guided Hemodynamic ManagemenT in Patients Having Major Abdominal Surgery: the UPRIGHT Randomized Feasibility Trial

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 116 (estimated)
• Sponsor: Universitätsklinikum Hamburg-Eppendorf · Academic / Other
• Sex: All
• Age: 45 Years
• Healthy volunteers: Not accepted

Summary

We will perform this single-center pilot trial to determine if the intraoperative urethral perfusion index is higher in patients assigned to maintaining postinduction baseline urethral perfusion index than in patients assigned to routine care (with blinded urethral perfusion index monitoring). As pre-planned substudies, we will also assess the agreement between a) urethral perfusion index-derived pulse rate and heart rate measured with an electrocardiogram and b) between the urethral perfusion index and the peripheral perfusion index.

Conditions

• Urethral Perfusion Index
• Tissue Perfusion
• Microcirculation

Interventions

Type	Name	Description
DEVICE	urethal perfusion index monitoring	The urethral perfusion index will be monitored using the IKORUS System (Vygon, Écouen, France)

Timeline

• Start date: 2025-01-21
• Primary completion: 2025-06-30
• Completion: 2025-07-31
• First posted: 2025-01-29
• Last updated: 2025-02-21

Locations

2 sites across 1 country: Germany