Clinical Trials Directory

Trials / Completed

CompletedNCT06799546

A Phase III Study to Evaluate the Efficacy and Safety of HSK39297 in Patients With Paroxysmal Nocturnal Hemoglobinuria Who Are Naive to Complement Inhibitor Therapy

A Phase III, Multicenter, Randomized, Open Label, Active-Controlled Study to Evaluate the Efficacy and Safety of HSK39297 Tablets in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) Who Are Naive to Complement Inhibitor Therapy

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
73 (actual)
Sponsor
Haisco Pharmaceutical Group Co., Ltd. · Industry
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate the efficacy and safety of HSK39297 tablets compared to eculizumab in Patients with PNH who Are Naive to Complement Inhibitor Therapy.

Conditions

Interventions

TypeNameDescription
DRUGHSK39297 tablets200mg QD for 24 weeks
DRUGEculizumab InjectionEculizumab Injection for 24 weeks

Timeline

Start date
2025-02-13
Primary completion
2025-11-05
Completion
2025-11-05
First posted
2025-01-29
Last updated
2025-12-22

Locations

2 sites across 1 country: China

Source: ClinicalTrials.gov record NCT06799546. Inclusion in this directory is not an endorsement.

A Phase III Study to Evaluate the Efficacy and Safety of HSK39297 in Patients With Paroxysmal Nocturnal Hemoglobinuria W (NCT06799546) · Clinical Trials Directory