NCT06798025

Three Different Modalities for Treatment of Inflammatory Punctal Stenosis

Comparative Study Between Three Different Modalities for Treatment of Inflammatory Punctal Stenosis

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Tanta University · Academic / Other
• Sex: All
• Age: 33 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

This study aimed to compare the efficacy of three various modalities of treatment of inflammatory punctal stenosis (Punctal dilatation alone, combined punctal dilatation with topical medications, or peri-punctal injection of Triamcinolone acetonide)

Detailed description

Acquired punctal stenosis is a condition in which the external opening of the lacrimal canaliculus, located in the nasal part of the palpebral margin, is narrowed or occluded. This condition results from chronic inflammation of the external punctum, leading to gradual fibrotic changes in the ostium, followed by progressive occlusion of the duct. Different modalities were described for the treatment of acquired punctual stenosis. Repeated dilatation of the stenotic punctum is a simple procedure that may provide temporary improvement of the symptoms, but restenosis is common unless additional procedures are performed. Many other methods were used to augment punctual size, including 1-snip, 2-snip, and 3-snip punctoplasty, supplemented with adding sutures or Mini-Monoka insertion and punch punctoplasty.

Conditions

• Modalities
• Treatment
• Inflammatory Punctal Stenosis

Interventions

Type	Name	Description
PROCEDURE	Punctal dilation	Patients were treated with punctal dilatation only.
DRUG	Punctal dilation and topical medication	Patients were treated with a combination of punctal dilation and topical medication in the form of preservative-free steroid eye drops based on dexamethasone sodium phosphate (0.1%) and preservative-free artificial tears based on sodium hyaluronate, polyethylene, and propylene Glycol.
DRUG	Triamcinolone acetonide	Patients were treated with a peri-punctual injection of Triamcinolone acetonide.

Timeline

• Start date: 2023-07-20
• Primary completion: 2024-06-30
• Completion: 2024-06-30
• First posted: 2025-01-29
• Last updated: 2025-01-29

Locations

1 site across 1 country: Egypt