NCT06796205

Evaluation of the Photoprotection Efficacy of Three Sunscreen Products Under Visible Light Exposure.

Assessment of the Protective Effects of Three Sunscreen Products on Visible Light Induced Pigmentation Compared with an Untreated Control Zone

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 20 (actual)
• Sponsor: Cosmetique Active International · Industry
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

To evaluate the protective effect of three sunscreens products on the pigmentation caused by visible light in comparison to an untreated control zone in healthy volunteers.

Detailed description

The sunscreens usually used as photoprotectors are known to protect in the UV domain (UVB and UVA). However, until recently visible light (400-700 nm) was considered as devoid of any photobiological effects on cutaneous tissue. Over the last two decades, with the development of photodynamic therapies and various dermatological treatments using visible laser light, several studies have reconsidered the cutaneous effect of visible light on the skin, in particular the induction of pigmentation. The aim of this study was to assess the ability of sunscreens with a protective efficacy in the UV domain to prevent the pigmentation induced by Visible Light.

Conditions

• Visible Light Exposure on Healthy Back Skin

Interventions

Type	Name	Description
OTHER	Treated zones exposed with Visible Light source	The treated zones were exposed to Visible Light to induce skin pigmentation (144J/cm2), 15 to 30 minutes after application.
OTHER	Untreated zone exposed with Visible Light source	The untreated zone was exposed to Visible Light to induce skin pigmentation (144J/cm2), as the same time as the treated zones.

Timeline

• Start date: 2021-06-09
• Primary completion: 2021-07-16
• Completion: 2021-07-16
• First posted: 2025-01-28
• Last updated: 2025-01-28

Locations

1 site across 1 country: France