NCT06796153

Photoprotection Efficacy of Different Topical Agents Under Visible Light Exposure

Assessment of the Protective Effect of Different Topical Agents on Visible Light Induced Pigmentation Compared with a Not Treated Control Zone

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 33 (actual)
• Sponsor: Cosmetique Active International · Industry
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

To evaluate the protective effect of seven sunscreens on the pigmentation induced by visible light in comparison to an untreated control zone in healthy volunteers

Detailed description

The sunscreens usually used as photoprotectors are known to protect in the UV domain (UVB and UVA). However, until recently visible light (400-700 nm) was considered as devoid of any photobiological effects on cutaneous tissue. Over the last two decades, with the development of photodynamic therapies and various dermatological treatments using visible laser light, several studies have reconsidered the cutaneous effect of visible light on the skin, in particular the induction of pigmentation. The study intends to evaluate and to compare with a non-treated control zone and between them, the efficacy of photoprotective effect of different products after visible light exposure, between \[400-700nm\].

Conditions

• Visible Light Exposure on Healthy Back Skin

Interventions

Type	Name	Description
OTHER	Visible Light Exposure - Treated zones	The treated zones were exposed to Visible Light to induce skin pigmentation (144J/cm2), 15 to 30 minutes after application.
OTHER	Visible Light Exposure - Untreated zone	The untreated zone was exposed to Visible Light to induce skin pigmentation (144J/cm2), as the same time as the treated zones.

Timeline

• Start date: 2021-04-23
• Primary completion: 2021-06-18
• Completion: 2021-06-18
• First posted: 2025-01-28
• Last updated: 2025-01-30

Locations

1 site across 1 country: Romania