Clinical Trials Directory

Trials / Recruiting

RecruitingNCT06794996

Inaxaplin in Participants With Proteinuric APOL1 Mediated Kidney Disease With or Without Comorbidities

A Phase 2b, Open-label Study to Evaluate the Efficacy and Safety of Inaxaplin in Subjects With Proteinuric APOL1-mediated Kidney Disease With or Without Comorbidities That May Independently Contribute to Chronic Kidney Disease

Status
Recruiting
Phase
Phase 2
Study type
Interventional
Enrollment
45 (estimated)
Sponsor
Vertex Pharmaceuticals Incorporated · Industry
Sex
All
Age
18 Years – 67 Years
Healthy volunteers
Not accepted

Summary

The purpose of the study is to evaluate the efficacy, safety, and tolerability of Inaxaplin (IXP) in participants with proteinuric APOL1- mediated kidney disease (AMKD).

Conditions

Interventions

TypeNameDescription
DRUGInaxaplinTablets for Oral Administration.

Timeline

Start date
2025-02-04
Primary completion
2026-12-30
Completion
2026-12-30
First posted
2025-01-27
Last updated
2026-04-08

Locations

35 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT06794996. Inclusion in this directory is not an endorsement.