NCT06794424

Impact of Ziwig Endotest® on the Management of Patients With Clinical Symptoms of Endometriosis Inconsistent With Their Imaging Work-up

Impact of Ziwig Endotest® on the Decision and Management of Patients With Chronic Disabling Pelvic Pain Strongly Suggestive of Endometriosis and Presenting With a Negative or Uncertain Baseline Imaging Workup

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 2,503 (actual)
• Sponsor: ZIWIG · Industry
• Sex: Female
• Age: 18 Years – 43 Years
• Healthy volunteers: Not accepted

Summary

The goal of this study is to evaluate the impact of Ziiwg Endotest on patient management decisions before and after the test. The main questions it aims to answer are: * Does the test reduce the intention and number of laparoscopies in women whose decision to undergo laparoscopy was made before the test result was obtained? * Does the test change management decisions in women with no prior indication for diagnostic laparoscopy? Study will compare the patient management decision before and after the test. The acts and procedures performed as part of this research are : * Aa saliva sampling (Ziwig Endotest) at inclusion * A mutidisciplinary meeting post test (if applicable) * Completion at inclusion and 6 month of a quality-of-life questionnaire (EHP-5) * Completion at inclusion and 6 month of a VAS for pain * Completion at inclusion and 6 month of a Likert satisfaction scale * A test results Announcement consultation * A visit at 6 months.

Conditions

• Endometriosis

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Ziwig Endotest®	Saliva sampling for Endometriosis diagnostic

Timeline

• Start date: 2025-03-14
• Primary completion: 2026-09-01
• Completion: 2026-09-01
• First posted: 2025-01-27
• Last updated: 2026-03-25

Locations

1 site across 1 country: France