Trials / Recruiting
RecruitingNCT06792721
MEASUREMENT OF CIRCULATING MUTATION BURDEN
EVALUATION OF CANCER RISK BY MEASUREMENT OF CIRCULATING MUTATIONAL BURDEN IN CARRIERS OF A GENETIC PREDISPOSITION
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 30 (estimated)
- Sponsor
- Centre Francois Baclesse · Academic / Other
- Sex
- Female
- Age
- 30 Years – 50 Years
- Healthy volunteers
- Accepted
Summary
Cancer-free women with a hereditary predisposition to breast and/or ovarian cancer
Detailed description
This proof-of-concept trial will be conducted with family members being monitored for a predisposition to breast and/or ovarian cancer linked to a BRCA1/2 gene mutation. The study will be proposed to two sisters from the same sibling: * one is a carrier of the genetic mutation * and the other not, Blood tests will evaluate the Mutation Burden cfMB
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| GENETIC | Mutation Burden cfMB analysis | Blood samples will be collected (one time only) |
Timeline
- Start date
- 2025-07-04
- Primary completion
- 2027-07-15
- Completion
- 2027-12-30
- First posted
- 2025-01-27
- Last updated
- 2025-07-08
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT06792721. Inclusion in this directory is not an endorsement.