NCT06790953

Efficacy of Novel Titania Nanoparticles Enriched Mouth Wash in Treating Dentine Hypersensitivity

Clinical Efficacy of Novel Biogenically Fabricated Titania Nanoparticles Enriched Mouth Wash in Treating the Tooth Dentine Hypersensitivity: A Randamized Clinical Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 130 (actual)
• Sponsor: Pakistan Institute of Medical Sciences · Other Government
• Sex: All
• Age: 20 Years – 50 Years
• Healthy volunteers: Accepted

Summary

Randomized Clinical trial to compare the reduction in dentin hypersensitivity after incorporating biogenically fabricated titania nanoparticles enriched Mouth Wash and Conventional Mouth Wash.Participants ranging between 20-50 years were allocated in two groups. Group A will use Conventional Mouth Wash without Nanoparticles. Group B will use titania nanoparticles enriched Mouth Wash. Both will use them for three months and then their VAS scoring will be checked.

Detailed description

In this study Novel biogenically fabricated titania nanoparticle reinforced Mouth Wash will be evaluated for dentine sensitivity . Participants following Inclusion criteria will be allocated in this study by Consecutive random sampling technique. Participants will be divided into two groups i.e Group-A and Group-B with dentin sensitivity of 30-80. Group A will be given Conventional Mouth Wash for three months and Group-B will be given titania nanoparticles enriched Mouth Wash for three months for the sensitivity. Sensitivity will be assessed using Visual analog scale (VAS) mean score after 1 month and then three months.

Conditions

• Dentine Hypersensitivity

Interventions

Type	Name	Description
PROCEDURE	Group- A Conventional Sensed Mouth Wash	In Group- A Conventional Sensed Mouth Wash will be used for treatment of Dentin hypersensitivity. Visual Analogue scoring system will be used to calculate the dentin hypersensitivity.
PROCEDURE	Group-B Novel Titania nanoparticles enriched Mouth Wash	In Group-B Novel Titania nanoparticles enriched Mouth wash will be used to treat the Dentin hypersensitivity. Visual Analogue scoring system will be used to calculate the dentin hypersensitivity.

Timeline

• Start date: 2024-06-13
• Primary completion: 2024-12-03
• Completion: 2024-12-03
• First posted: 2025-01-24
• Last updated: 2025-02-04

Locations

1 site across 1 country: Pakistan