NCT06789770

Nasal vs Oral Breathing in Drug Induced Sleep vs Natural Sleep

The Impact of Nasal Versus Oral Breathing on Measures of Drug-Induced Sleep Endoscopy

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 50 (estimated)
• Sponsor: University of Pennsylvania · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This project will provide important new information regarding (1) the relationship between route of breathing and airway collapsibility and (2) whether route of breathing during DISE (Drug-Induced Sleep Endoscopy) is representative of natural sleep.

Detailed description

As part of standard of care, a drug-induced sleep endoscopy will be done, where route of breathing will be determined as a percentage of total breaths (during baseline, lateral sleep and maneuver). As part of the research procedure, an in-laboratory Polysomnogram will be conducted as study procedure including a oronasal pressure signal cannula to assess route of breathing.

Conditions

• Sleep Apnea, Obstructive

Timeline

• Start date: 2024-11-20
• Primary completion: 2026-12-01
• Completion: 2026-12-01
• First posted: 2025-01-23
• Last updated: 2026-03-13

Locations

1 site across 1 country: United States