NCT06789575

Comparison of Bupivacaine Wound Infiltration Versus Wound Instillation to Minimize Postoperative Pain After Thyroid Surgery

• Status: Not Yet Recruiting
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 102 (estimated)
• Sponsor: Assiut University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Pain management following thyroidectomies, which can cause mild to moderate postoperative pain, particularly in the first 24 hours following surgery, has received little attention . The incision of the wound, neck hyperextension, retraction of the wound margins during surgery, and dissection are the main reasons of post-thyroidectomy discomfort . After thyroid surgery, pain management improves patients' quality of life and facilitates a speedy return to regular daily activities. the aim of the study to evaluate the effects of bupivacaine instillation after thyroidectomy against infiltration into the surgical field in order to reduce postoperative discomfort following thyroid surgery.

Detailed description

Pain management following thyroidectomies, which can cause mild to moderate postoperative pain, particularly in the first 24 hours following surgery, has received little attention . The incision of the wound, neck hyperextension, retraction of the wound margins during surgery, and dissection are the main reasons of post-thyroidectomy discomfort . After thyroid surgery, pain management improves patients' quality of life and facilitates a speedy return to regular daily activities.

Conditions

• Thyroid Surgery

Interventions

Type	Name	Description
DRUG	Bupivacaine	the patients will receive the content of a syringe (10 ml of bupivacaine 0.25%)
DRUG	Adrenaline	the patients will receive the content of a syringe 15 μg adrenaline
DRUG	Lidocaine (drug)	the patients will receive the content of a syringe 70 ml Lidocaine .

Timeline

• Start date: 2025-03-01
• Primary completion: 2026-03-01
• Completion: 2027-05-01
• First posted: 2025-01-23
• Last updated: 2025-01-23

Regulatory

• FDA-regulated drug study