NCT06789185

Effects of Esketamine at Subanesthetic Dose on Emergence Delirium in Preschool Children Undergoing Ambulatory Laparoscopic Surgery

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 96 (actual)
• Sponsor: Qiu jinpeng · Academic / Other
• Sex: All
• Age: 24 Months – 71 Months
• Healthy volunteers: Not accepted

Summary

Emergence delirium (ED) is a manifestation of acute postoperative brain dysfunction that occurs with a relatively high frequency after pediatric anesthesia. The incidence varies depending on the diagnostic criteria used and the combination of administered anesthetic drugs. The goal of this clinical trial is to investigate whether a subanesthetic dose of esketamine can reduce incidence of ED.

Conditions

• Inguinal Hernia

Interventions

Type	Name	Description
DRUG	0.1mg/kg esketamine	Intravenous injection 0.1mg/kg esketamine about 5min before the end of the surgery
DRUG	0.2mg/kg esketamine	Intravenous injection 0.2mg/kg esketamine about 5min before the end of the surgery
DRUG	0.1ml/kg normal saline	Intravenous injection 0.1ml/kg normal saline about 5min before the end of the surgery

Timeline

• Start date: 2025-02-07
• Primary completion: 2025-05-16
• Completion: 2025-05-16
• First posted: 2025-01-23
• Last updated: 2025-05-22

Locations

1 site across 1 country: China