Trials / Completed
CompletedNCT06787924
Impact of Collagen Supplements on Dermal Collagen in Plastic and Bariatric Surgery Patients
Effect of Collagen Supplements on Dermal Collagen Content Within Skin Biopsies of Plastic Surgery and Metabolic Bariatric Surgery Patients
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 102 (actual)
- Sponsor
- General Committee of Teaching Hospitals and Institutes, Egypt · Other Government
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Accepted
Summary
This study aims to evaluate the effects of oral collagen supplementation on dermal collagen content in skin biopsies of patients undergoing abdominoplasty. Using a randomized controlled trial (RCT) design, participants from metabolic bariatric surgery (MBS) and plastic surgery groups will receive either collagen supplements or a placebo for several weeks. Biopsies will be collected pre-intervention and during surgery to compare collagen levels between groups and to baseline. The primary objective is to determine if collagen supplementation significantly enhances dermal collagen deposition compared to placebo and initial levels.
Conditions
- Bariatric Surgery
- Abdominoplasty
- Collagen Synthesis
- Skin Physiology
- Randomized Controlled Trial
- Tissue Remodeling
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Collagen hydrolyzed peptides | bovine collagen peptides |
| DIETARY_SUPPLEMENT | Starch | Starch placebo |
Timeline
- Start date
- 2025-04-15
- Primary completion
- 2025-10-31
- Completion
- 2025-12-15
- First posted
- 2025-01-22
- Last updated
- 2026-02-17
Locations
1 site across 1 country: Egypt
Source: ClinicalTrials.gov record NCT06787924. Inclusion in this directory is not an endorsement.