Trials / Recruiting
RecruitingNCT06787066
Sympathetic Vascular Transduction Across the Menopause Transition: Contributing Mechanisms
- Status
- Recruiting
- Phase
- EARLY_Phase 1
- Study type
- Interventional
- Enrollment
- 75 (estimated)
- Sponsor
- University of Missouri-Columbia · Academic / Other
- Sex
- Female
- Age
- 18 Years – 70 Years
- Healthy volunteers
- Accepted
Summary
The investigators aim to assess the interactions between the sympathetic nervous system and the vasculature in women across the menopause transition to better understand why aging women have a higher risk of cardiovascular disease.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Propranolol Hydrochloride | Examine how IV propranolol impacts sympathetic transduction |
| DRUG | Phentolamine Injection | Examine how IV phentolamine impacts sympathetic transduction |
Timeline
- Start date
- 2025-07-10
- Primary completion
- 2026-12-01
- Completion
- 2026-12-01
- First posted
- 2025-01-22
- Last updated
- 2025-09-15
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT06787066. Inclusion in this directory is not an endorsement.