NCT06786403

The Effects of Bromelain Supplement in Patients with Diabetic Foot Ulcers

Investigating the Effectiveness of the Supplement Containing Enteric-coated Bromelain (Anaheal 1200 GDU) in Healing Wounds, Pain, and Inflammation in Patients Over 18 Years Old with Diabetic Foot Ulcers Compared to Placebo

• Status: Not Yet Recruiting
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 70 (estimated)
• Sponsor: Dr Azita Hekmatdoost · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study will be conducted on people over 18 with diabetic foot ulcers.. The first group will receive the standard treatment along with bromelain supplement and the second group will receive the standard treatment and placebo. The informed consent form prepared in advance will also be provided to the patients so that they are fully familiar with the study process. Wound surface area, rate of pain, rate of inflammatory factors (ESR and CRP) will be assessed at baseline and every two weeks.

Conditions

• Diabetic Foot Ulcer (DFU)

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Bromelain	Dietary Supplement: Bromelain 1000 mg/day
DIETARY_SUPPLEMENT	Placebo	Placebo (1000 mg/day)

Timeline

• Start date: 2025-03-01
• Primary completion: 2025-08-01
• Completion: 2025-10-01
• First posted: 2025-01-22
• Last updated: 2025-01-22

Locations

1 site across 1 country: Iran