NCT06786351

Impact of Right Atrial Occlusion on TEVAR Outcomes

Impact of Right Atrial Occlusion on TEVAR Outcomes: A Prospective Cohort Study

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: University of Calgary · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

Though the application of thoracic endovascular aortic repair (TEVAR) for treatment of aortic pathology is expanding, there remains a gap in the literature examining how intraoperative "reduction or elimination of aortic impulse" (REAI) techniques, in particular the use of right atrial occlusion, may impact patient important clinical outcomes. This study aims to provide prospective data from a large cohort of TEVAR patients to explore clinical outcomes following TEVAR procedures and, specifically, whether right atrial occlusion has significant impact on clinical outcomes, as compared to other REAI techniques. The results from this study may inform future perioperative TEVAR practices and improve TEVAR patient outcomes.

Conditions

• Thoracic Aortic Aneurysm
• Thoracic Aortic Dissection
• Thoracic Aorta Abnormality

Interventions

Type	Name	Description
PROCEDURE	Right atrial balloon occlusion	Thoracic endovascular aortic repair with right atrial balloon occlusion for reduction or elimination of aortic impulse and stent graft deployment in landing zones 0-3
PROCEDURE	Non right atrial balloon occlusion	Thoracic endovascular aortic repair not using right atrial balloon occlusion for reduction or elimination of aortic impulse and stent graft deployment in landing zones 0-3

Timeline

• Start date: 2025-09-01
• Primary completion: 2029-01-31
• Completion: 2029-01-31
• First posted: 2025-01-22
• Last updated: 2025-06-29