NCT06785753

Effectiveness of Cryotherapy on Endodontic Pain

Effectiveness of Intracanal Cryotherapy on Post Operative Pain After Root Canal Therapy in Patients with Symptomatic Apical Periodontitis

• Status: Recruiting
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Armed Forces Institute of Dentistry, Pakistan · Academic / Other
• Sex: All
• Age: 20 Years – 40 Years
• Healthy volunteers: Accepted

Summary

This is a randomized , prospective , control trial to assess the effectiveness of intracanal cryotherapy on post operative pain after root canal treatment in patients with symptomatic apical periodontitis

Detailed description

Diagnostic procedures to include patients history taking , clinical and radiographic with all findings being recorded in patients . patients diagnosed with symptomatic irreversible pulpitis with symptomatic apical periodontitis. patients will be asked to rate their pre treatment pain on visual analogue scale from 0-10 patients with pain score \<8 will be considered Anesthesia and isolation : after administration of local anesthesia , rubber dam application will be done Acess cavity : acess will be gained with round bur using air turbune handpiece with copious water cooling Working length : a size 10k file will be inserted into the canal to determine the working length with the help of radiograph Cleaning and shaping : Extirpation of pulp will be done followed by canal preparation with manual and endodontic motor using naocl and EDTA . final irrigation will be performed using 17% EDTA and 5.25% NaOCl Patients will be divided into 2 group in control group : final irrigation will be done using 5ml of saline at room temperature in cold group : final irrigation will be done using 5ml of cold saline at 2.5°C the solution will be stored in the refrigerator until use irrigation will be performed for 5 min in both groups using 27 G beveled needle tip inserted 2mm short of WL. Obturation ; In both groups , canals will be dried with paper points and obturated using gutta percha cones with zinc oxide eugenol sealer Restoration : acces cavity will be restroed with direct composite restoration or high viscosity glass ionomer cement each patient will be given instruction to acess the post operative pain .

Conditions

• Post Operative Pain

Interventions

Type	Name	Description
DRUG	Irrigation Solution	normal saline will be used as irrigation solution

Timeline

• Start date: 2024-11-07
• Primary completion: 2025-05-07
• Completion: 2025-05-08
• First posted: 2025-01-21
• Last updated: 2025-01-21

Locations

1 site across 1 country: Pakistan

Regulatory

• FDA-regulated drug study