NCT06785168

The Effect of Resistance Training on Sarcopenia in Older Heart Failure Patients

The Effects of Machined Based Resistance Training in Older Patients With Chronic Heart Failure With Sarcopenia

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 146 (estimated)
• Sponsor: Kieu Nguyen Dang Phuong · Academic / Other
• Sex: All
• Age: 60 Years
• Healthy volunteers: Not accepted

Summary

The goal of study is to evaluate the effects of an eight-week machine-based resistance training program on managing sarcopenia in older outpatients with chronic heart failure (HF) at Military Hospital 175.

Detailed description

The participants will be randomly assigned to two groups: One group received machine-based resistance training (MRT) at the hospital, while the other group received usual care (US). The outcomes will be measured in the participants after 8 weeks including handgrip strength, gait speed, performance on the five-times sit-to-stand test.

Conditions

• Sarcopenia in Elderly
• Chronic Heart Failure

Interventions

Type	Name	Description
OTHER	Machine-based Resistance Training	The participants will receive HF treatment as prescribed by cardiologists. If participants have any additional medical conditions, their existing medications or treatments should continue. They are also asked to maintain their usual physical activity, exercise routines, and dietary habits, without making changes outside of the study intervention. At the beginning, patients participating in resistance training should complete a pretest of one-repetition maximum (1-RM) to assess muscle strength, which will be used by a professional physical therapist to develop an individualized prescription. The specific movements are as follows: (1) leg press and (2) calf raise by Proxomed Compass 540 (Germany); (3) leg curl, (4) chest press, (5) push up, (6) seated row by HUR machine (US). During the 8 weeks, subjects will train 3 non-consecutive days/week with intensity 30%1-RM to 60% 1-RM, 3 sets/one excercise with 8-12 repetitions.

Timeline

• Start date: 2024-12-24
• Primary completion: 2026-12-31
• Completion: 2027-12-31
• First posted: 2025-01-21
• Last updated: 2026-02-17

Locations

2 sites across 1 country: Vietnam