NCT06782100

MRI Guided Management of Occlusive Peripheral Arterial Disease

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 175 (estimated)
• Sponsor: The Methodist Hospital Research Institute · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this observational study is to identify which plaque lesions in patients with peripheral arterial disease are impenetrable and to determine which devices minimize vessel wall injury. Patients undergoing intervention will have an MRI scan prior to their planned percutaneous vascular intervention to assess the plaque and predict procedural difficulty. Patients undergoing lower limb amputation due to peripheral arterial disease will have their limbs included into a second arm of the study The limb will undergo an MRI scan to assess the plaque. The investigator will then test two different devices and assess the effects of these devices on the vessel wall.

Detailed description

Please see attached study protocol.

Conditions

• Peripheral Vascular Diseases

Timeline

• Start date: 2024-07-01
• Primary completion: 2028-07-01
• Completion: 2029-06-01
• First posted: 2025-01-17
• Last updated: 2026-03-19

Locations

1 site across 1 country: United States