NCT06781892

Strategies for Defibrillation During Out-of-Hospital Cardiac Arrest

Strategies for Defibrillation During Out-of-Hospital Cardiac Arrest - A Randomized Clinical Trial

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 909 (estimated)
• Sponsor: Lars Wiuff Andersen · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The "Strategies for Defibrillation during Out-of-Hospital Cardiac Arrest" (STRAT-DEFI) trial is an investigator-initiated, individually randomized, 3-group clinical trial comparing standard anterior-lateral pad positioning with anterior-posterior positioning and double sequential defibrillation during adult out-of-hospital cardiac arrest.

Conditions

• Cardiac Arrest (CA)

Interventions

Type	Name	Description
OTHER	Anterior-lateral pad positioning	Defibrillation pads positioned anterior-lateral
OTHER	Anterior-posterior pad positioning	Defibrillation pads positioned anterior-posterior
OTHER	Double-sequential defibrillation	Combination of anterior-lateral and anterior-posterior pad positioning for a total of 4 pads and 2 shocks.

Timeline

• Start date: 2025-03-15
• Primary completion: 2028-03-01
• Completion: 2029-03-01
• First posted: 2025-01-17
• Last updated: 2025-05-23

Locations

6 sites across 1 country: Denmark