NCT06781827

Research on the Use of Probiotics in the Prevention and Treatment of Inflammatory Bowel Disease

Application Research of Lactobacillus Reuteri in the Treatment of Inflammatory Bowel

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Wecare Probiotics Co., Ltd. · Industry
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This project involves the use of oral Lactobacillus reuteri as an adjunct therapy for 8 weeks. Endoscopic observation of intestinal inflammation will be conducted at 1 month, 3 months, 6 months, and 12 months after the administration of the drug. Intestinal fluid will be collected endoscopically for 16S RNA analysis to assess changes in the gut microbiota. Inflammatory changes in the patients will be detected through peripheral blood tests, and fecal calprotectin levels will be measured to evaluate the progression of the disease.

Conditions

• Inflammatory Bowel Disease

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Probiotic	The experimental phase of the study lasts 8 weeks and each patient will be visited 4 times (January, March, June, and December).
DIETARY_SUPPLEMENT	Maltodextrin	The experimental phase of this study had last 8 weeks and each patient will make 4 visits (January, March, June, and December).

Timeline

• Start date: 2025-01-01
• Primary completion: 2025-10-30
• Completion: 2025-12-30
• First posted: 2025-01-17
• Last updated: 2025-04-04

Locations

1 site across 1 country: China