NCT06781034

Descriptive Study on MRI Contrast of Acute Cerebral Hemorrhage in Different Microangiopathies

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 128 (estimated)
• Sponsor: Centre Hospitalier Universitaire de Nīmes · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Cerebral haemorrhage represents a minority of acute vascular syndromes (less frequent than ischemic stroke, at around 20%), but with a therapeutic impasse, having no specific treatment. Arterial contrast ("spot sign") within the hematoma has been described in CT scans as a risk factor for further enlargement and poor prognosis. An equivalent marker has also been described in gadolinium-enhanced MRI. By studying the radiological appearance of gadolinium "spot signs" on MRI, which has better parenchymal resolution, the researchers propose to retrace the phenomenology of the acute phase of cerebral hemorrhage in order to better estimate the risk of radiological aggravation by subgroup, which could serve as a target population for future therapeutic trials.

Conditions

• Cerebral Hemorrhage
• Acute Lobar Haematoma

Interventions

Type	Name	Description
OTHER	None, pure observational study	None, pure observational study

Timeline

• Start date: 2025-02-01
• Primary completion: 2025-12-01
• Completion: 2025-12-01
• First posted: 2025-01-17
• Last updated: 2025-01-17