NCT06778655

Propolis in Primary Herpetic Gingivostomatitis

Propolis in Management of Primary Herpetic Gingivostomatitis Measuring the Level of INF-γ in Saliva. Randomized Clinical Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Fayoum University · Academic / Other
• Sex: All
• Age: 3 Years – 8 Years
• Healthy volunteers: Not accepted

Summary

The purpose of the present study is to investigate the efficacy of 5% propolis gel in the treatment of primary herpetic gingivostomatitis in children and its effect on salivary IFN-γ levels.

Conditions

• Herpetic Gingivostomatitis

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	5% propolis gel	5% propolis gel (prepared according to Joshy et al. 2018) Joshy A, Doggalli N, Patil K, Kulkarni PK. To Evaluate the Efficacy of Topical Propolis in the Management of Symptomatic Oral Lichen Planus: A Randomized Controlled Trial. Contemp Clin Dent. 2018 Jan-Mar;9(1):65-71.
OTHER	Placebo gel	placebo mucoadhesive gel having the same flavor, consistency, and color as the propolis.

Timeline

• Start date: 2024-10-10
• Primary completion: 2025-01-15
• Completion: 2025-01-15
• First posted: 2025-01-16
• Last updated: 2025-01-30

Locations

1 site across 1 country: Egypt