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Not Yet RecruitingNCT06777459

Study of Nitrate-Rich Juice on Cognitive Function in Heavy Alcohol Drinkers: a Two-Stage Adaptive Design Real-World Clinical Trial

Status
Not Yet Recruiting
Phase
N/A
Study type
Interventional
Enrollment
43 (estimated)
Sponsor
Peking University Sixth Hospital · Academic / Other
Sex
All
Age
Healthy volunteers
Not accepted

Summary

It is known that alcohol consumption can lead to cognitive impairment and dysregulation of inflammatory responses. A preliminary randomized controlled trial conducted by our research team has suggested that nitrate may improve cognition in hospitalized patients with alcohol dependence. To further expand the population and applicability, this study aims to explore the effects of nitrate on cognition in a real-world population of heavy drinkers. The researchers have designed a two-stage clinical trial: the first stage involves the analysis of existing data, and the second stage will recruit 43-54 new participants for a 14-day dietary inorganic nitrate (nitrate-rich beetroot juice, \~750 mg NO3- /d) intervention.

Detailed description

No comments

Conditions

Interventions

TypeNameDescription
DIETARY_SUPPLEMENTNitrate-rich beetroot juiceNitrate-rich beetroot juice, \~750 mg NO3- /d

Timeline

Start date
2025-01-15
Primary completion
2025-12-31
Completion
2025-12-31
First posted
2025-01-15
Last updated
2025-01-15

Source: ClinicalTrials.gov record NCT06777459. Inclusion in this directory is not an endorsement.

Study of Nitrate-Rich Juice on Cognitive Function in Heavy Alcohol Drinkers: a Two-Stage Adaptive Design Real-World Clin (NCT06777459) · Clinical Trials Directory