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Trials / Active Not Recruiting

Active Not RecruitingNCT06774313

A Study to Assess the Adverse Events and How Subcutaneous (SC) Injections and Intravenous (IV) Infusions of ABBV-142 Move Through the Body of Healthy Adult Participants

A Phase 1a Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Single Ascending Doses of ABBV-142 in Healthy Adult Subjects and Single Doses of ABBV-142 in Healthy Adult Asian Subjects

Status
Active Not Recruiting
Phase
Phase 1
Study type
Interventional
Enrollment
73 (actual)
Sponsor
AbbVie · Industry
Sex
All
Age
18 Years – 55 Years
Healthy volunteers
Accepted

Summary

This study is designed to assess the pharmacokinetic properties, safety, tolerability, and immunogenicity of ABBV-142 and determine whether predicted efficacious exposures can be safely achieved in humans.

Conditions

Interventions

TypeNameDescription
DRUGABBV-142Intravenous (IV) Infusion
DRUGABBV-142Subcutaneous (SC) Injection
DRUGPlaceboIV Infusion
DRUGPlaceboSC Injection

Timeline

Start date
2025-01-22
Primary completion
2026-04-01
Completion
2026-04-01
First posted
2025-01-14
Last updated
2026-02-17

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT06774313. Inclusion in this directory is not an endorsement.

A Study to Assess the Adverse Events and How Subcutaneous (SC) Injections and Intravenous (IV) Infusions of ABBV-142 Mov (NCT06774313) · Clinical Trials Directory