NCT06770166

The Effect of Chamomile on Healing After Tooth Extraction

The Effect of Chamomile on Healing After Tooth Extraction: a Retrospective Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 120 (actual)
• Sponsor: reyhansaglam · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

After impacted wisdom tooth extraction, patients frequently complain of pain, edema, and limited mouth opening. After the procedure, patients are routinely recommended to use chlorhexidine and physiological serum-based mouthwashes. The antibacterial and anti-inflammatory effects of warm chamomile tea have been reported in the literature. In addition, the neuroprotective, antiallergic, antioxidant, antiseptic and spasmolytic properties of chamomile have been reported. The aim was to compare the effects of these gargles in terms of pain, mouth opening, burning sensation in the mouth, edema, and discoloration of the tongue and teeth.

Detailed description

The study was planned to be applied to 120 patients, 40 in each group. In the ASA 1 group, the mouth opening of the patients was recorded before the tooth extraction procedure. Impacted teeth were extracted using Ultracain D-S Forte (Articaine HCl: 40mg/ml, Epinephrine HCl: 0.012 mg/ml) as a local anesthetic. Dental units were prepared under sterile conditions. The patients were covered with a sterile drape. The lower wisdom tooth was extracted with open (surgical) extraction. The mucoperisoteal flap was lifted with a number 15 surgical scalpel, and the tooth was extracted using round and fissure-tipped steel burs with a handpiece. After tooth extraction, if there was granulation tissue in the extraction socket, it was curetted and irrigated with physiological serum \[sodium chloride: 0.009 g/ml, sodium 154 (mEq/I), chloride 154 (mEq/I)\]. After bleeding control, patients were given written and verbal postoperative advice. Antibiotics and analgesics were prescribed to patients, chlorhexidine gargle was recommended to 30 patients, saline gargle to 30 patients, and chamomile tea gargle to 30 patients. Patients were given VAS pain scores, numbered 0-10, to record for 7 days after extraction. Patients were called back to the clinic on the 2nd and 7th days after tooth extraction to assess pain, burning sensation and color change in the tongue, mouth opening, and edema. Sutures were removed on the 7th postoperative day.

Conditions

• Tooth Extraction Status Nos

Interventions

Type	Name	Description
OTHER	Physiological serum mouthwash	Physiological serum contains sodium chloride : 0.009 g/ml, sodium 154 (mEq/I), chloride 154 (mEq/I)\].
OTHER	Chlorhexidine mouthwash	Chlorhexidine mouthwash contains 0.12% chlorhexidine digluconate and 0.15% benzydamine hydrochloride.
OTHER	Chamomile mouthwash	Chamomile mouthwash contains 10% chamomile in physiological serum.

Timeline

• Start date: 2019-03-01
• Primary completion: 2024-10-26
• Completion: 2024-10-26
• First posted: 2025-01-13
• Last updated: 2025-01-13

Locations

1 site across 1 country: Turkey (Türkiye)