Trials / Recruiting
RecruitingNCT06769191
Clinical Study on the Safety and Efficacy of CD7 CAR-T Cell Sequential Allo-HSCT and Kidney Transplantation in the Treatment of SIOD
Clinical Study on the Safety and Efficacy of CD7 CAR-T Cell Sequential Allogeneic Hematopoietic Stem Cell Transplantation and Kidney Transplantation in the Treatment of Schimke Immuno-osseous Dysplasia
- Status
- Recruiting
- Phase
- EARLY_Phase 1
- Study type
- Interventional
- Enrollment
- 20 (estimated)
- Sponsor
- Zhejiang University · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- Not accepted
Summary
A Clinical Study on the Safety and Effectiveness of CD7 CAR-T Cell Sequential Allo-HSCT and Kidney Transplantation in the treatment of Schimke immuno-osseous dysplasia
Detailed description
This is a single-arm, open-label, dose-escalation clinical trial to evaluate the safety and efficacy of CD7 CAR-T Cell Sequential Allo-HSCT and Kidney Transplantation in patients with Schimke immuno-osseous dysplasia. It is planned to enroll 20 participants in this trial.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BIOLOGICAL | CD7 CAR-T cells injection | Intravenous infusion, single dose |
| PROCEDURE | Allo-HSCT | allogeneic hematopoietic stem cell transplantation |
| PROCEDURE | Kidney Transplantation | Kidney Transplantation |
Timeline
- Start date
- 2025-01-30
- Primary completion
- 2028-01-30
- Completion
- 2028-01-30
- First posted
- 2025-01-10
- Last updated
- 2025-01-20
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT06769191. Inclusion in this directory is not an endorsement.