NCT06768203

The Effect of Umbilical Vein Catheterization on Splanchnic Oxygenation in Preterm Infants

The Effect of Umbilical Vein Catheterization on Splanchnic Oxygenation

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 48 (actual)
• Sponsor: Eskisehir Osmangazi University · Academic / Other
• Sex: All
• Age: 1 Day – 3 Months
• Healthy volunteers: Not accepted

Summary

Objectives: This study aimed to assess the impact of umbilical vein catheter (UVC) placement on splanchnic oxygenation in preterm infants. Methods: In our single-center, prospective, observational cohort study, near-infrared spectroscopy probes were placed to monitor regional splanchnic oxygen saturation (rSO2S) and calculate fractional tissue oxygen extraction (FOE) in preterm infants (GA \< 34 weeks, BW 1000-2000 g) for one week post-stabilization. Gestational age-matched UVC (+) and (-) Groups were clinically and physiologically compared, before and after UVC placement/removal.

Detailed description

The purpose of this study was to evaluate how the insertion of an umbilical vein catheter (UVC) affected the splanchnic oxygenation of preterm newborns..

Conditions

• Feeding Intolerance
• Necrotising Enterocolitis Neonatal

Interventions

Type	Name	Description
OTHER	umbilical vein catheterization	In our NICU, UVC placement is a sterile bedside procedure carried out by pediatric residents, neonatology fellows, and neonatology specialists, using polyurethane, single-lumen catheters sized according to the infant's weight: 3.5 Fr for those under 1500 g and 5 Fr for those over 1500 g. Catheter placement is performed using the Modified Shukla-Ferrara Formula
OTHER	Control	No umbilical vein catheter was inserted in these infants.

Timeline

• Start date: 2023-02-09
• Primary completion: 2024-02-01
• Completion: 2024-04-01
• First posted: 2025-01-10
• Last updated: 2025-01-10

Locations

1 site across 1 country: Turkey (Türkiye)