Trials / Active Not Recruiting
Active Not RecruitingNCT06767020
Comparative Study on AQP4 Antibody Detection Methods
A Multi-center Comparative Real-World Study on AQP4 Antibody Detection Methods Using Live Cell and Fixed Cell-Based Assay Technologies
- Status
- Active Not Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 120 (estimated)
- Sponsor
- First Affiliated Hospital of Chongqing Medical University · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
This study aims to determine which method is more suitable for clinical application by comparing the sensitivity, specificity, and accuracy of serum AQP4-IgG detection using live cell CBA and fixed cell CBA methods, thereby improving the diagnostic accuracy of neuromyelitis optica spectrum disorders (NMOSD).
Detailed description
This is a multi-center comparative real-world study on AQP4 Antibody Detection Methods Using Live Cell and Fixed Cell-Based Assay Technologies. This study aims to determine which method is more suitable for clinical application by comparing the sensitivity, specificity, and accuracy of serum AQP4-IgG detection using live cell CBA and fixed cell CBA methods, thereby improving the diagnostic accuracy of neuromyelitis optica spectrum disorders (NMOSD). One hundred and twenty patients from 3 centres in China will be enrolled.
Conditions
Timeline
- Start date
- 2023-11-11
- Primary completion
- 2025-01-27
- Completion
- 2025-01-27
- First posted
- 2025-01-09
- Last updated
- 2025-01-09
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT06767020. Inclusion in this directory is not an endorsement.