NCT06766474

The Rule of Bupivacaine Hydrochloride in Skin Graft Donor Site

Bupivacaine Hydrochloride-Soaked Dressing Versus Subcutaneous Infiltration for Postoperative Analgesia in Skin Graft Donor Site: a Randomized Controlled Clinical Trial

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 90 (actual)
• Sponsor: Minia University · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

Split Thickness Skin Graft is frequently utilized for reconstructing skin loss of various causes. Unfortunately, the donor site of the STSG has an unavoidable, annoying post-operative pain

Detailed description

The primary objective of this study was to compare the efficacy of bupivacaine hydrochloride-soaked dressing versus bupivacaine HCL subcutaneous infiltration for postoperative donor site pain control for patients undergoing STSG procedures. The patients were divided in 3 equal groups, investigated soaked dressing vs subcutaneous infiltration vs conventional dressing .

Conditions

• Skin Graft Complications
• Pain Management

Interventions

Type	Name	Description
DRUG	Bupivacain	to our knowledge, this study is the 1st to compare the efficacy of bupivacaine hydrochloride-soaked dressing versus subcutaneous infiltration for postoperative donor site pain control for patients undergoing STSG procedures.

Timeline

• Start date: 2023-03-01
• Primary completion: 2024-10-15
• Completion: 2024-10-30
• First posted: 2025-01-09
• Last updated: 2025-01-13

Locations

1 site across 1 country: Egypt

Regulatory

• FDA-regulated drug study