NCT06765603

Evaluating the Efficacy of the Combination of Multi-zonal Contact Lens and Atropine for Controlling Myopia Progression

• Status: Not Yet Recruiting
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 180 (estimated)
• Sponsor: Singapore National Eye Centre · Other Government
• Sex: All
• Age: 7 Years – 13 Years
• Healthy volunteers: Not accepted

Summary

The aim of the study is to explore efficacy of combination Atropine and multifocal CL. Randomized Control Trial including 4 arms: Atropine / multizonal CL; Atropine/ SV CL, Placebo drop/ multizonal CL; Placebo drop/ SV CL. Followed over 1 year with outcome measure of change in spherical equivalent and axial length.

Detailed description

see above

Conditions

• Myopia

Interventions

Type	Name	Description
DRUG	Atropine 0.025%	Atropine 0.025%
DEVICE	Multizonal contact lens	Multizonal CL
DRUG	Placebo	Placebo
DEVICE	Single vision Contact lens	Single vision contact lens

Timeline

• Start date: 2025-02-01
• Primary completion: 2028-12-31
• Completion: 2029-12-31
• First posted: 2025-01-09
• Last updated: 2025-01-09