NCT06764550

Molecular and Microbiota Signatures Underlying Colonic Diverticular Disease

Molecular and Microbiota Signatures Underlying Colonic Diverticular Disease - Caratterizzazione Dei Meccanismi Molecolari e Del Microbiota Nella Malattia Diverticolare Del Colon

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 150 (actual)
• Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The pathogenesis of diverticular disease is likely multifactorial in origin. This project aims to study the involvement of environmental factors in the pathophysiology of diverticular disease, the underlying molecular mechanisms, and alterations in the microbiota.

Detailed description

The pathogenesis of diverticular disease is likely multifactorial in origin. Some studies have demonstrated the role of genetic factors, while others have highlighted the role of environmental factors. The present project aims to study the involvement of environmental factors in the pathophysiology of diverticular disease, the underlying molecular mechanisms, and alterations in the microbiota.

Conditions

• Diverticular Disease of Colon

Interventions

Type	Name	Description
OTHER	This is an observational study, participants are not assigned an intervention as part of the study.	This is an observational study, participants are not assigned an intervention as part of the study.

Timeline

• Start date: 2020-03-05
• Primary completion: 2024-07-31
• Completion: 2025-03-31
• First posted: 2025-01-08
• Last updated: 2025-01-08

Locations

1 site across 1 country: Italy