Clinical Trials Directory

Trials / Available

AvailableNCT06761976

Expanded Access to Provide Sevabertinib (BAY 2927088) for the Treatment of Locally Advanced or Metastatic NSCLC With HER2 Mutation

An Expanded Access Program to Provide Oral Sevabertinib (BAY 2927088) in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) Harboring an HER2 (Human Epidermal Growth Factor Receptor 2) Activating Mutation

Status
Available
Phase
Study type
Expanded Access
Enrollment
Sponsor
Bayer · Industry
Sex
All
Age
18 Years
Healthy volunteers

Summary

The purpose of this Expanded Access Program (EAP) is to provide access to sevabertinib, for participants previously treated with locally advanced or metastatic non-small cell lung cancer (NSCLC) with mutations in the human epidermal growth factor receptor 2 (HER2) gene, which have no other therapeutic option.

Conditions

Interventions

TypeNameDescription
DRUGSevabertinibSevabertinib is self-administered by the patient BID (twice a day) as tablets for oral administration

Timeline

First posted
2025-01-07
Last updated
2026-03-30

Source: ClinicalTrials.gov record NCT06761976. Inclusion in this directory is not an endorsement.