NCT06756009

Evaluation of Chronic Liver Disease Condition and Transplant Prognosis Assisted by Eye Biological Parameters

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 500 (estimated)
• Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This study investigates the correlation between ocular biological characteristics and overall conditions before and after liver transplantation by collecting ocular biological characteristics. Explore whether it is possible to construct a clinical prediction model for liver transplantation by incorporating ocular biometric features, in order to optimize disease management before and after liver transplantation.

Detailed description

This study is a bidirectional cohort study, which retrospectively analysed data from a prospective database to construct a model, and prospectively collected patient information from preoperative to postoperative for model improvement and validation.

Conditions

• Diagnostic Techniques, Ophthalmological
• Liver Transplantation
• Liver Cirrhoses

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Ophthalmic examination	Various ophthalmic examination modalities, including slit lamp photography, fundus photography, optical coherence tomography imaging and optical coherence tomography angiography, etc.
DIAGNOSTIC_TEST	General Condition Examination	Various general condition examination, including blood pressure measurement, blood glucose testing, blood routine examination, coagulation function test, liver function test, etc.

Timeline

• Start date: 2022-03-01
• Primary completion: 2025-12-30
• Completion: 2026-12-30
• First posted: 2025-01-01
• Last updated: 2025-01-01

Locations

1 site across 1 country: China