NCT06755996

Dexmedetomidine Nasal Spray and Pediatric Bronchoscopy

Combination of Dexmedetomidine Nasal Spray and Remimazolam for the Treatment of Pediatric Bronchoscopy

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 150 (actual)
• Sponsor: Tongji Hospital · Academic / Other
• Sex: All
• Age: 2 Years – 6 Years
• Healthy volunteers: Not accepted

Summary

To observe the sedative effect of using dexmedetomidine nasal spray combined with remimazolam for pediatric bronchoscopy diagnosis and treatment, provide a safer and more comfortable anesthesia plan for pediatric bronchoscopy diagnosis and treatment

Detailed description

Dexmedetorimidine nasal spray is a new dosage form, which is simple and easy to achieve sedative and anti-anxiety effects by nasal spray mucosa. In the dose range from 50 to 100 μ g, the sedation effect increased dose-dependent, with\> 2 μ g / kg administered, and the child could be successfully separated within 45min.Our study is to observe the sedative effect of using dexmedetomidine nasal spray combined with remimazolam for pediatric bronchoscopy diagnosis and treatment, provide a safer and more comfortable anesthesia plan for pediatric bronchoscopy diagnosis and treatment

Conditions

• Fiberoptic Bronchoscopy

Interventions

Type	Name	Description
DRUG	Dexmedetomidine injection	Dexmedetomidine injection 3μg/kg
DRUG	Remimazolam	remimazolam 0.5mg / kg

Timeline

• Start date: 2025-01-07
• Primary completion: 2025-08-31
• Completion: 2025-08-31
• First posted: 2025-01-01
• Last updated: 2026-01-27

Locations

1 site across 1 country: China