NCT06755814

ItAlian ReGistry Of pNeumoniA in immUnocompromised paTients (ARGONAUT)

Community-acquired Pneumonia in Immunosuppressed Adult Patients: Observational, Perspective Study, ItAlian ReGistry Of pNeumoniA in immUnocompromised paTients (ARGONAUT)

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 1,298 (estimated)
• Sponsor: Societa Italiana di Pneumologia · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This multicentric, prospective study aims at: evaluating the prevalence, etiology, characteristics, and 1one-year outcomes of immunocompromised patients hospitalized for Community-Acquired Pneumonia (CAP); conducting biochemical, microbiological and genetic analysis on collected samples.

Detailed description

Primary endpoint: Collection of in- hospitalisation mortality for all causes in immunocompromised patients with CAP enrolled. Secondary endpoints: Collection of data on admission and during hospitalisation to evaluate clinical response to empirical treatments (including antibiotic therapy) related to severity of disease and microbiological etiology. Prevalence of cardiovascular events and all-cause mortality during hospitalization or after discharge. Biochemical, microbiological and genetic analysis on collected samples.

Conditions

• Community Acquired Pneumonia (CAP)

Timeline

• Start date: 2025-08-11
• Primary completion: 2028-12-01
• Completion: 2028-12-01
• First posted: 2025-01-01
• Last updated: 2025-11-18

Locations

1 site across 1 country: Italy