NCT06755333

Oral Hygiene Management of Hematologic Patients Undergoing Auto-transplantation

Oral Hygiene Management of Hematologic Patients Undergoing Auto-transplantation: Observational Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 35 (actual)
• Sponsor: University of Pisa · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

This study assessed the effectiveness of a preventive protocol that included oral hygiene measures, patient education, and motivational strategies in individuals eligible for hematopoietic stem cell transplantation (HSCT).

Detailed description

At baseline (T0), the patient underwent a professional oral hygiene session prior to initiating chemotherapy, as part of the routine pre-transplant protocol. During this session, periodontal charting was completed, and patients were provided with oral hygiene instructions. Following admission, patients received pre-transplant conditioning chemotherapy. Once engraftment of the transplant was confirmed by the Hematology Unit (9 days after engraftment), clinical parameters were reassessed (T1).

Conditions

• Hematopoietic Stem Cell Transplantation

Interventions

Type	Name	Description
BEHAVIORAL	Oral hygiene motivation	the patient underwent a professional oral hygiene session before starting chemotherapy, as part of the routine pre-transplant procedure. Patients then received oral hygiene instructions.

Timeline

• Start date: 2023-01-09
• Primary completion: 2023-09-29
• Completion: 2024-05-31
• First posted: 2025-01-01
• Last updated: 2025-01-01

Locations

1 site across 1 country: Italy