Clinical Trials Directory

Trials / Completed

CompletedNCT06749782

Semi-automatic Measurement of Renal Volume at CT Angiography to Plan Repair of Aortic Aneurysms in Patients With Horseshoe Kidney.

Semi-automatic Measurement of Renal Volume at Computed Tomography (CT) Angiography to Plan Repair of Aortic Aneurysms in Patients With Horseshoe Kidney: a Retrospective Study

Status
Completed
Phase
Study type
Observational
Enrollment
5 (actual)
Sponsor
IRCCS San Raffaele · Academic / Other
Sex
All
Age
18 Years – 100 Years
Healthy volunteers

Summary

The horseshoe kidney (HK) is a congenital anomaly in which the kidneys are fused in front of the anterior aortic wall in its most common form. The association of abdominal aortic aneurysm (AAA) and horseshoe kidney (HK) is a rare and challenging condition, occurring in less than 0.2% of all AAA cases. In these cases, open surgery is still widely practiced in many centers, with either a transperitoneal or retroperitoneal approach. Typically, several polar arteries arise from the distal abdominal aorta or the iliac arteries to perfuse the HK. A key consideration for the surgery is whether or not to preserve the vascularization of the variant kidney. Preserving them can be challenging, but removing them can lead to a significant reduction in renal volume and subsequent loss of function. In open surgery repair, it is recommended to reanastomose as many arteries as possible to the prosthesis, even though this introduces additional technical challenges, especially in emergency situations. Computed Tomography Angiography (CTA) is the best diagnostic test for performing a preoperative vascular assessment. The purpose of the present study is to develop a semi-automated model on preoperative CCTA to measure the volume of parenchyma perfused by each artery to determine whether or not these should be preserved. The model will be validated on post-surgical CCTA in patients with HK treated for AAA. Customized use of this tool could be a valuable method in surgical decision making, determining which arteries can be made safe during surgery and addressing a rare but complex clinical need.

Conditions

Interventions

TypeNameDescription
RADIATIONTCRadiation: Computed Tomography (CT)

Timeline

Start date
2024-11-27
Primary completion
2024-12-20
Completion
2024-12-20
First posted
2024-12-27
Last updated
2024-12-27

Locations

1 site across 1 country: Italy

Source: ClinicalTrials.gov record NCT06749782. Inclusion in this directory is not an endorsement.