NCT06747494

General vs Spinal in Total Joint Arthroplasty (TJA)

General Versus Spinal Anesthesia for Total Joint Arthroplasty: A Prospective Randomized Trial

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 2,396 (estimated)
• Sponsor: University of Miami · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this research is to compare post-operative outcomes from patients undergoing TJA. The study team wants to learn about outcomes like length of hospital stay, post-operative pain scores, post-operative nausea, deep and superficial surgical site infection, periprosthetic fracture (a broken bone that occurs around an orthopaedic implant), implant dislocation, readmission rates, and revision rates.

Conditions

• Knee Osteoarthritis
• Hip Osteoarthritis

Interventions

Type	Name	Description
PROCEDURE	General Anesthesia	Participants will receive a one-time general anesthesia dose during the total joint arthroplasty procedure as per standard of care.
PROCEDURE	Spinal Anesthesia	Participants will receive a one-time spinal anesthesia dose during the total joint arthroplasty procedure as per standard of care.

Timeline

• Start date: 2025-02-01
• Primary completion: 2030-03-01
• Completion: 2030-03-01
• First posted: 2024-12-24
• Last updated: 2026-03-18

Locations

1 site across 1 country: United States