NCT06744101

Comparative Evaluation of Diffusion Weighted MRI And Ultrasonography In The Detection of Breast Lesions

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 108 (actual)
• Sponsor: Superior University · Academic / Other
• Sex: Female
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

This study aims to conduct a comparative evaluation of Diffusion Weighted MRI (DW-MRI) and Ultrasonography (US) in detecting breast lesions. Breast cancer remains a leading cause of cancer-related deaths among women worldwide, necessitating efficient and accurate diagnostic methods. Ultrasonography, a commonly used imaging modality, provides valuable insights into breast lesions but has limitations in sensitivity and specificity.

Detailed description

Diffusion Weighted MRI, on the other hand, shows potential for higher accuracy in identifying malignant versus benign lesions due to its ability to assess tissue cellularity and integrity non-invasively. This research will involve a specified number of female participants within a defined age range, focusing on the comparative effectiveness, sensitivity, and specificity of DW-MRI and US. The findings are expected to contribute valuable insights into optimizing breast cancer diagnostic protocols, ultimately aiding in earlier detection, better patient outcomes, and possibly reducing the need for invasive biopsy procedures.

Conditions

• Breast LN

Interventions

Type	Name	Description
RADIATION	Evaluate the effectiveness of Diffusion Weighted MRI (DWI) in detecting breast lesions.	Assess the sensitivity, specificity, and diagnostic accuracy of DWI compared to Ultrasonography (USG) for benign and malignant lesions.
RADIATION	Compare Sensitivity and Specificity of DWI and USG	Analyze which modality performs better in lesion detection based on sensitivity and specificity.

Timeline

• Start date: 2024-02-28
• Primary completion: 2024-07-01
• Completion: 2025-03-01
• First posted: 2024-12-20
• Last updated: 2024-12-20

Locations

1 site across 1 country: Pakistan