Clinical Trials Directory

Trials / Completed

CompletedNCT06742944

Draw-10: A Weekly Blood Draw Study to Understand the Biological Variability of Plasma pTau-217

Status
Completed
Phase
Study type
Observational
Enrollment
100 (actual)
Sponsor
Banner Health · Academic / Other
Sex
All
Age
50 Years – 80 Years
Healthy volunteers
Accepted

Summary

This is an observational study that will serially collect 10 plasma samples over the course of 9 weeks from the same individuals to assess fluctuations in blood biomarker results.

Detailed description

Blood biomarkers offer a less invasive and cheaper method for identifying Alzheimer's disease (AD)-related changes. Already, blood biomarkers for AD are being adopted by clinical practice and their use will only expand in coming years. However, blood biomarkers are susceptible to fluctuations not yet well characterized. Such fluctuations, although rarely observed in current research settings, may influence the biological evaluation of dementia once implemented into routine settings. The study at present aims to identify how blood biomarkers fluctuate over a short period of time in the same individual and assess drivers of these fluctuations.

Conditions

Timeline

Start date
2025-01-27
Primary completion
2025-08-27
Completion
2025-11-30
First posted
2024-12-19
Last updated
2025-12-09

Locations

2 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT06742944. Inclusion in this directory is not an endorsement.