NCT06739304

The Effectiveness of Mindfulness-based Relapse Prevention

The Effectiveness of Mindfulness-based Relapse Prevention: A Randomized Controlled Trial Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 1,200 (actual)
• Sponsor: Sir Run Run Shaw Hospital · Academic / Other
• Sex: Female
• Age: 25 Years – 57 Years
• Healthy volunteers: Accepted

Summary

This study developed a Mindfulness-based Relapse Prevention targeting craving. Based on the Randomized Controlled Trial design, 600 adult USD females and 600 adult USD males with methamphetamine, heroin, or ketamine in Intervention group(MBI) , the matched 250 subjects in Control group and 250 healthy matched controls (HC) participated in this study, 1200 adult USD subjects of Intervention group received the 8-week Group mindfulness intervention performed by psychiatrists. SUD patients were assessed three times, before, during(1-2 weeks after the MBI began), and after the intervention by a variety of clinical variables, cognitive task(reginal segmental task),fMRI and blood test to verify the effectiveness of the intervention method, attempting to expand the model of addiction and mindfulness.

Detailed description

The Group Mindfulness-based intervention adhered to structured formal procedures, conducted by psychiatrists, and was scheduled once a week, where each session spans for two hours, interspersed with a 10-minute break. Starting from the second intervention, the previous intervention's contents and home practice were reviewed at the beginning of each subsequent intervention. Based on the Randomized Controlled Trial design, the evaluation time nodes for clinical variables, cognitive task(reginal segmental task),fMRI and blood test were baseline (before intervention), 1-2 weeks after intervention began, and after intervention. All clinical variable scales were presented in paper form, the questions were clearly explained by researchers.

Conditions

• Substance Use Disorder

Interventions

Type	Name	Description
BEHAVIORAL	Mindfulness-based Relapse Prevention	250 adult USD females of Intervention group received the 8-week Group mindfulness intervention performed by psychiatrists.

Timeline

• Start date: 2023-06-10
• Primary completion: 2023-08-05
• Completion: 2023-11-10
• First posted: 2024-12-18
• Last updated: 2025-04-01

Locations

1 site across 1 country: China