NCT06738342

Clinical Efficacy of a Chlorhexidine-based Mouth-rinse Containing Citrus Aurantium Amara

Clinical Efficacy of a Chlorhexidine-based Mouth-rinse Containing Citrus Aurantium Amara in Patients Undergoing Periodontal Surgery: a Triple-blind, Parallel-arm, Randomized Controlled Trial

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 32 (estimated)
• Sponsor: University of Roma La Sapienza · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The primary objective of the study is the evaluation of efficacy of a mouthwash cointaining Chlorexidine (CHX) 0.09% + HA + Citrox (test group) on the quality of wound healing and the presence plaque formation and gingival inflammation in the post-surgical phase. Futhermore stains, discolorations and adverse effects will be eventually recorded. Control group will be represented by the use of a CHX 0.12% mouthwash.

Conditions

• Wound Healing

Interventions

Type	Name	Description
OTHER	CHX 0.09% + Citrox + HA	The patient will use the assigned mouthwash starting 24 hours after the surgical procedures and continuing twice a day for 14 days.
DRUG	CHX 0.12%	The patient will use the assigned mouthwash starting 24 hours after the surgical procedures and continuing twice a day for 14 days.

Timeline

• Start date: 2024-12-01
• Primary completion: 2025-03-01
• Completion: 2025-04-01
• First posted: 2024-12-17
• Last updated: 2024-12-20

Locations

1 site across 1 country: Italy