Trials / Completed
CompletedNCT06735274
Transcranial Doppler (TCD) Ultrasound and Cognition in Cerebral Vascular Disease. (SUNRISE)
Transcranial Doppler (TCD) Ultrasound for Predicting and Understanding Cognitive Decline in Cerebral Vascular Disease.
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 517 (actual)
- Sponsor
- Universidade do Porto · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
This study aims to contribute to the identification of factors that may be predictive of cognitive function and to provide data on cerebral hemodynamic in ischemic and haemorrhagic stroke. This study will prospectively study cerebral autoregulation, neurovascular coupling and microembolic signs in cerebrovascular patients with ischemic and haemorrhagic stroke and its relationship with cognitive function and functional recovery
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | Cerebral Autoregulation (CAR) | Cerebral Autoregulation (CAR) is the mechanism capable of maintaining cerebral blood flow constant despite fluctuations in blood pressure. The evaluation of dynamic CAR (dCAR) with spontaneous blood pressure variations allows it to be applied in acute and non-collaborating patients |
| DIAGNOSTIC_TEST | Neurovascular coupling (NVC) | Neurovascular coupling (NVC) is the relationship between neural activity and cerebral blood flow, allowing this activity to be evaluated in spatiotemporal terms . |
| DIAGNOSTIC_TEST | Microembolic signals (MES) | Microembolic signals (MES) |
| DIAGNOSTIC_TEST | Montreal Cognitive Assessment (MoCA) | Montreal Cognitive Assessment (MoCA) |
| DIAGNOSTIC_TEST | Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) | Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) |
| DIAGNOSTIC_TEST | Instrumental Activities of Daily Living Scale (IADL) | Instrumental Activities of Daily Living Scale (IADL) |
| DIAGNOSTIC_TEST | Modified Rankin Scale for Neurologic Disability (mRS) | Modified Rankin Scale for Neurologic Disability (mRS) |
Timeline
- Start date
- 2020-10-15
- Primary completion
- 2023-05-30
- Completion
- 2023-08-30
- First posted
- 2024-12-16
- Last updated
- 2024-12-16
Locations
1 site across 1 country: Portugal
Source: ClinicalTrials.gov record NCT06735274. Inclusion in this directory is not an endorsement.