NCT06734975

Effect of Superior Laryngeal Nerve Blocks on Patient Outcomes in Laryngeal Surgery

Effect of Intraoperative Superior Laryngeal Nerve Blocks on Patient Outcomes in Microdirect Laryngoscopy for Benign Vocal Fold Lesions: A Randomized Trial

• Status: Recruiting
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 28 (estimated)
• Sponsor: Rutgers, The State University of New Jersey · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Patients undergoing surgery on their vocal cord will either receive a numbing injection to their throat or a saline injection during surgery. Symptoms such as how much coughing or pain patients have after surgery, as well as whether patient's voice gets better will be interrogated.

Conditions

• Vocal Cord Disease
• Vocal Cord Polyp
• Vocal Cord Cyst

Interventions

Type	Name	Description
DRUG	Superior laryngeal nerve block - Intervention (Bupivacaine and triamcinolone acetonide suspension)	Patients will receive a superior laryngeal nerve block consisting of 1 ml of 0.25% bupivacaine and 1mL of triamcinolone acetate 40 mg/ml to the neck on the side of the vocal cord lesion during their surgery.
DRUG	Superior laryngeal nerve block - Placebo (saline)	Patients will receive a saline placebo of 2mL saline to the neck on the side of the vocal cord lesion during their surgery.

Timeline

• Start date: 2025-07-11
• Primary completion: 2026-12-01
• Completion: 2026-12-01
• First posted: 2024-12-16
• Last updated: 2026-01-15

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study