NCT06734546

The Effect of Exercise on the Brain in Type 2 Diabetes

The Effect of Exercise of High vs. Moderate Intensity on the Brain in Type 2 Diabetes

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 75 (estimated)
• Sponsor: Hasselt University · Academic / Other
• Sex: All
• Age: 30 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to learn if exercise training of high or moderate intensity is most optimal to improve brain health and prevent neurodegeneration in type 2 diabetes patients. The main question it aims to answer is: What is the effect of exercise training of high vs. moderate intensity on brain metabolism, brain perfusion, and cognition in type 2 diabetes? Researchers will compare the exercise training groups to a control group without exercise training to determine the effect of exercise training on the brain in type 2 diabetes. Participants will exercise for 6 months, 3 times per week. Before and after these 6 months, they will undergo: * a brain MRI scan * cognitive tests * blood sampling

Conditions

• Type 2 Diabetes

Interventions

Type	Name	Description
OTHER	Exercise intervention	The exercise intervention entails 6 months of supervised exercise on a hometrainer at high or moderate intensity, 3 times per week

Timeline

• Start date: 2024-11-08
• Primary completion: 2027-08-01
• Completion: 2027-08-01
• First posted: 2024-12-16
• Last updated: 2026-03-31

Locations

1 site across 1 country: Belgium