NCT06732648

The Efficacy and Safety of HRS8179 in Severe Cerebral Edema Following Large Hemispheric Infarction

The Efficacy and Safety of Intravenous HRS8179 for the Prevention and Treatment of Severe Cerebral Edema Following Large Hemispheric Infarction: a Multicenter, Randomized, Double-blind, Placebo-controlled, Phase II/III Clinical Trial

• Status: Recruiting
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 725 (estimated)
• Sponsor: Beijing Suncadia Pharmaceuticals Co., Ltd · Industry
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The study is being conducted to evaluate the efficacy, and safety of HRS8179 injection in preventing and treating severe cerebral edema after large area cerebral infarction in the cerebral hemisphere

Conditions

• Severe Cerebral Edema Following Large Hemispheric Infarction

Interventions

Type	Name	Description
DRUG	HRS8179 injection	HRS8179 injection; high dose
DRUG	HRS8179 blank preparation.	HRS8179 blank preparation.

Timeline

• Start date: 2025-02-07
• Primary completion: 2027-06-01
• Completion: 2027-09-01
• First posted: 2024-12-13
• Last updated: 2025-08-22

Locations

1 site across 1 country: China