Trials / Completed
CompletedNCT06725043
Ultrasound Acupuncture for Oxaliplatin-induced Peripheral Neuropathy in Colorectal Cancer Patients
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 60 (actual)
- Sponsor
- Cairo University · Academic / Other
- Sex
- All
- Age
- 20 Years – 70 Years
- Healthy volunteers
- Not accepted
Summary
The current study was conducted to examine the effect of ultrasound acupuncture for oxaliplatin-induced peripheral neuropathy in colorectal cancer patients.
Detailed description
Oxaliplatin is platinum-based chemotherapy most usually used for the treatment of metastatic colorectal cancer, this drug can produce a cumulative and dose-limiting distal sensory neuropathy affecting the majority of oxaliplatin-treated patients. Despite intense investigation at the preclinical and clinical levels, no treatment can be suggested for the prevention of OIPN. Since acupuncture has proven effective in alleviating the severity of peripheral nerve neuropathy, as has ultrasound. This systematic review was conducted to test the ability of ultrasound acupuncture in decreasing neuropathy-related symptoms induced by oxaliplatin-based chemotherapies in colorectal cancer patients
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | Therapeutic ultrasound | Pulsed therapeutic ultrasound (1 MHz , 50% duty cycle and intensity gradually increased till the patient felt a deqi sensation).Each point was stimulated by ultrasound for 5 minutes at bilateral acupuncture points of PC6, PC7, BL60 and KI1(3 times / week for 4 weeks). |
| DEVICE | Placebo therapeutic ultrasound | patients were received placebo therapeutic ultrasound at bilateral acupuncture points of PC6, PC7, BL60, and KI. |
| OTHER | Traditional physical therapy program | Strengthing exercise, balance training, stretching exercises and home exercise program and education |
Timeline
- Start date
- 2023-07-01
- Primary completion
- 2024-08-30
- Completion
- 2024-12-03
- First posted
- 2024-12-10
- Last updated
- 2024-12-10
Locations
1 site across 1 country: Egypt
Source: ClinicalTrials.gov record NCT06725043. Inclusion in this directory is not an endorsement.