NCT06723145

Optimal PERioperative Antiplatelet Therapy Investigation ON Abdominal Surgery After Coronary Stent Implantation

• Status: Recruiting
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 1,200 (estimated)
• Sponsor: Kyoto University · Academic / Other
• Sex: All
• Age: 20 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to evaluate the impact of perioperative aspirin continuation on clinical outcomes in patients with a history of coronary stent implantation who are scheduled for abdominal surgery.

Detailed description

PCI with coronary stent implantation is performed for a huge number of patients with coronary artery disease. Approximately 20% of these patients undergo non-cardiac surgery within three years after PCI. However, there is a scarcity of clinical evidence regarding the efficacy of perioperative aspirin continuation on cardiovascular events.

Conditions

• Antiplatelet Agents
• Perioperative Care

Interventions

Type	Name	Description
DRUG	Aspirin	perioperative aspirin continuation
DRUG	Aspirin interruption	Aspirin interruption 5-7 days before surgery

Timeline

• Start date: 2025-01-20
• Primary completion: 2027-02-28
• Completion: 2027-03-31
• First posted: 2024-12-09
• Last updated: 2025-02-11

Locations

1 site across 1 country: Japan